Aggregate Gene Set List with Matching Coexpression in Parallel

This function swaps gene sets in geneSetList with those from sampled_geneSetList (with coexpression matched, see resample_geneSetList_matching_coexp) and aggregates gene set scores in parallel.

Usage

aggregate_geneSetList_matching_coexp(
  geneList.true,
  geneSetList,
  sampled_geneSetList,
  method,
  n_cores = 1
)

Arguments

geneList.true

A m x 1 matrix of true association values. Each row corresponds to a gene, and the column contains the association values between the gene and the brain.

geneSetList

A list of gene sets.

sampled_geneSetList

A list of sampled gene sets.

method

The method to be used for aggregation.

n_cores

Number of cores to use for parallel processing. Default is 1. If set to 0, it uses all available cores minus one.

Value

A list of aggregated gene set scores.